On October 24, 2007, it was announced that Romário would take charge of his first match as the interim manager of Vasco da Gama against Club América of Mexico in the return leg of their Copa Sudamericana quarter final and he would also participate on the field as a player. Romário, then 41 years of age, replaced Celso Roth as the manager of Vasco da Gama, and also played the match against Club América at the same time. The Vasco da Gama president Eurico Miranda declared to Globo Online that Romário would be in charge of the team for the match, but it is likely to only be temporarily. On February 6, Romario objected to Miranda's intervention in team selection, so was dismissed, but remained contracted to Vasco as a player.
On December 4, 2007, Romário announced he had tested positive for finasteride (aka Propecia) after a match against Palmeiras on October 28. He claims it was in an anti-baldness treatment; however, the drug is banned as it is a masking agent for anabolic steroids.